Would you start or sit this guy in Week 1 vs. the Colts? Click through the gallery to find out what our fantasy football expert says.

START Matt Ryan, QB, Falcons at Chiefs. He and his elite receivers have been locked-in all preseason. Kansas City may be playing without its best corner, Brandon Flowers (foot).

START DeAngelo Williams, RB, Panthers at Buccaneers. Normally, I avoid this backfield like the plague. But Jonathan Stewart (ankle) could very well be out, leaving Cam Newton as Williams’ primary competition for carries and rushing scores.

START Kevin Smith, RB, Lions vs. Rams. His preseason ankle injury appears to have subsided, though it’s only a matter of time before Smith’s next nagging injury. Better start him now while Mikel Leshoure is serving the his two-game suspension.

START Antonio Brown, WR, Steelers at Broncos. Uncertainty in the backfield and Mike Wallace’s extended holdout should conspire to make Brown the busiest man on the field. Already a favorite of Big Ben’s, Brown will stake his claim to the lead receiver.

START Reggie Wayne, WR, Colts at Bears. Chicago’s pass defense was their Achilles’ heel in 2011, and the Colts’ rushing “attack” won’t pose much of a threat to the Bears’ front four. Plus, Andrew Luck and Company will likely be playing from behind.

START Matt Schaub, QB, Texans.

SIT Michael Turner, RB, Falcons at Chargers. Aside from a 1-yard scoring plunge in Week 2, Turner has been horrible. Mix in his early morning DUI arrest after the Monday nighter, and Turner should be sentenced to your bench.

START Rashard Jennings, RB, Jaguars

START Torrey Smith, WR, Ravens.

START Brandon Lloyd, WR, Patriots

START Lance Moore, WR, Saints

START Pierre Garcon, WR, Redskins

START Malcom Floyd, WR, Chargers

START Nate Washington, WR, TItans.

START Jay Cutler, QB, Bears

SIT Peyton Manning, QB, Broncos vs. Steelers. He’ll probably make me look like an idiot for doubting him, but I would be very reluctant to start Manning in his first “real” game action against the mighty Pittsburgh defense.

SIT BenJarvus Green-Ellis, RB, Bengals at Ravens. I have high expectations for the Law Firm in Cincinnati, but the matchup in Baltimore worries me. Green-Ellis should get the bulk of the carries, and Terrell Suggs’ absence from the Ravens’ front four will

SIT Cedric Benson, RB, Packers vs. 49ers. One of the safest start/bench calls last season was whichever RB was playing the Niners. There’s little reason to think that will change now, especially when Benson is starting his first game in Green Bay’s pass-f

SIT Anquan Boldin, WR, Ravens vs. Bengals. The torch is being passed in Baltimore from the veteran Boldin to the upstart Torrey Smith. Against the solid Cincinnati secondary, Boldin is unlikely to see much daylight.

SIT Vincent Jackson, WR, Buccaneers vs. Panthers. Josh Freeman struggled throughout the preseason, not to mention most of 2011, and the Bucs’ new offensive scheme is centered on the running game.

START Ryan Fitzpatrick, QB, Bills

SIT Russell Wilson, QB Seahawks

SIT Carson Palmer, QB, Raiders

SIT Josh Freeman, QB, Bucs

7. Robert Griffin III (57)

SIT Adrian Peterson, RB, Vikings

SIT Donald Brown, RB, Colts

SIT Ronnie Hillman, RB, Broncos

SIT Maurice Jones-Drew, RB, Jaguars

SIT Ronnie Brown, RB, Chargers

SIT Beanie Wells, RB, Cardinals

SIT Montario Hardesty, RB, Browns

SIT Evan Royster, RB, Redskins

SIT Rashard Mendenhall, RB, Steelers

SIT Trent RIchardson, RB, Browns

SIT Lagarrette Blount, RB, Bucs

SIT Peyton Hillis, RB, Chiefs

SIT Santonio Holmes, WR, Jets

SIT Sidney Rice, WR, Seahawks